HFSA ePoster Library

Advanced Heart Failure Therapy In The Middle East; Case Series, With Clinical, Imaging & Pathological Correlation, From A Nascent Program
HFSA ePoster Library. Hashmani S. 09/10/21; 343640; 81
Dr. Shahrukh Hashmani
Dr. Shahrukh Hashmani
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Abstract
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Shahrukh Hashmani, Anas El Zouhbi, Yosef Manla, Richard Ferrer, Walid El Tahlawy, Guirgis Gabra, Iman Mukhtar Hamour, Fahad AlSindi, Feras Bader, Hussam Ghalib.

Cleveland Clinic Abu Dhabi, ABU DHABI, UNITED ARAB EMIRATES.
 

Background: The global prevalence of heart failure continues to increase, with more patients presenting with advance heart failure that requires durable left ventricular (LVAD) placement and/or orthotopic heart transplantation (OHT).

Aim: To describe the characteristics (clinical, imaging, pathological) and outcomes of patients undergoing LVAD/OHT at Cleveland Clinic Abu Dhabi (CCAD); a relatively new program from the UAE.

Methods: Retrospective chart review of all patients who had undergone LVAD/OHT at CCAD. The time period is 5/2017-current. Clinical data, imaging findings (echo, cardiac MRI, cardiac PET) and pathology findings were analysed and correlated.
 

Results:

Baseline characteristics and long-term outcomes are shown in Table 1. Non-Ischemic Cardiomyopathy was the predominant type of cardiomyopathy requiring LVAD or OHT. Ischemic Cardiomyopathy, as an etiology, was disproportionately-noted in patients who received LVAD therapy compared to those who underwent OHT. Myocarditis was disproportionately-noted in patients who underwent OHT, compared to the patients receiving LVAD.

Table 2 shows the percentage of concordance or discordance between clinical, imaging and pathological diagnoses. The patients are separated by treatment strategy (LVAD, BTT or OHT). Importantly, clinical and imaging diagnoses of myocarditis were less likely to be corroborated on pathological examination. The concordance was excellent in the OHT group, modest in the LVAD group and poor in the BTT group.

Conclusions: We report the positive outcomes of patients seeking LVAD/OHT at our young program from the UAE. In spite of the low INTERMACS profiles, the outcomes are comparable to those reported to international databases. Concordance between clinical, imaging and pathological diagnoses of cardiomyopathy varied based on the treatment strategy.

Shahrukh Hashmani, Anas El Zouhbi, Yosef Manla, Richard Ferrer, Walid El Tahlawy, Guirgis Gabra, Iman Mukhtar Hamour, Fahad AlSindi, Feras Bader, Hussam Ghalib.

Cleveland Clinic Abu Dhabi, ABU DHABI, UNITED ARAB EMIRATES.
 

Background: The global prevalence of heart failure continues to increase, with more patients presenting with advance heart failure that requires durable left ventricular (LVAD) placement and/or orthotopic heart transplantation (OHT).

Aim: To describe the characteristics (clinical, imaging, pathological) and outcomes of patients undergoing LVAD/OHT at Cleveland Clinic Abu Dhabi (CCAD); a relatively new program from the UAE.

Methods: Retrospective chart review of all patients who had undergone LVAD/OHT at CCAD. The time period is 5/2017-current. Clinical data, imaging findings (echo, cardiac MRI, cardiac PET) and pathology findings were analysed and correlated.
 

Results:

Baseline characteristics and long-term outcomes are shown in Table 1. Non-Ischemic Cardiomyopathy was the predominant type of cardiomyopathy requiring LVAD or OHT. Ischemic Cardiomyopathy, as an etiology, was disproportionately-noted in patients who received LVAD therapy compared to those who underwent OHT. Myocarditis was disproportionately-noted in patients who underwent OHT, compared to the patients receiving LVAD.

Table 2 shows the percentage of concordance or discordance between clinical, imaging and pathological diagnoses. The patients are separated by treatment strategy (LVAD, BTT or OHT). Importantly, clinical and imaging diagnoses of myocarditis were less likely to be corroborated on pathological examination. The concordance was excellent in the OHT group, modest in the LVAD group and poor in the BTT group.

Conclusions: We report the positive outcomes of patients seeking LVAD/OHT at our young program from the UAE. In spite of the low INTERMACS profiles, the outcomes are comparable to those reported to international databases. Concordance between clinical, imaging and pathological diagnoses of cardiomyopathy varied based on the treatment strategy.

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