HFSA ePoster Library

Heart Failure Clinic No-show Rates And Effect On Heart Failure Hospitalizations: A Real-World Experience From The Middle East
HFSA ePoster Library. Alsindi F. 09/10/21; 343536; 298
Fahad Alsindi
Fahad Alsindi
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Abstract
Discussion Forum (0)
Introduction: Functional status is associated with poor health outcomes, including quality of life. The Short Physical Performance Battery (SPPB) is commonly used to assess functional status. However, there are limited data describing quantifiable functional status limitations in Black and Hispanic patients with stable congestive heart failure. We hypothesized that in a Black and Hispanic outpatient population with heart failure, low functional capacity, as determined by low SPPB score, would be associated with worse quality of life.
Methods: The multicenter, prospective, Screening for Cardiac Amyloidosis in Minority Populations (SCAN-MP) study identified Black and Hispanic subjects with heart failure, collected baseline characteristics, and measured SPPB. Quality of life was measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ). SPPB scores were stratified into severe functional deficit (0-6), mild functional deficit (7-9) and no functional deficit (10-12).
Results: Of 220 patients in the study, 201 (91.3%) completed the SPPB. SPPB score was associated with the overall KCCQ score and with multiple subdomains of the KCCQ, but not exclusively with physical limitation (Table 1). Patients with low SPPB scores were more likely to be older, female, have higher BMI and NYHA class, less education, more comorbidities, and worse Six-Minute Walk Test (Table 2).
Conclusion: Among Black and Hispanic outpatients with stable heart failure, stepwise decrements in functional status, as defined by the SPPB, are associated with overall KCCQ score, and scores across a variety of sub-domains. These findings suggest that targeted interventions to improve patients’ functional status could broadly benefit quality of life.
Baseline Characteristics by SPPB Category
Severe Limitations (n=65)Mild Limitations (n=84)No Limitations (n=52)P value
Age, mean (SD)73.9 (7.9)71.2 (8.7)69.6 (7.5)0.016
Gender, n (%)<0.001
Male24 (36.9)51 (60.7)37 (71.2)
Female41 (63.1)33 (39.3)15 (28.8)
BMI, mean (SD)35.2 (8.2)32.0 (6.7)33.0 (7.3)0.030
Education, n (%)0.016
Less Than High School32 (50.0)22 (26.5)11 (21.6)
High School23 (35.9)33 (39.8)22 (43.1)
College6 (9.4)22 (26.5)15 (29.4)
Graduate3 (4.7)4 (4.8)3 (5.9)
Number of Comorbidities, mean (SD)6.5 (1.7)5.9 (2.0)5.1 (1.8)<0.001
Echo Left Ventricular Ejection Fraction, mean (SD)55.1 (14.0)58.3 (10.6)54.0 (11.1)0.106
NYHA Class (%)<0.001
Class I4 (6.2)18 (21.7)15 (28.8)
Class II28 (43.8)46 (55.4)32 (61.5)
Class III31 (48.4)19 (22.9)5 (9.6)
Class IV1 (1.6)0 (0.0)0 (0.0)
Six-Minute Walk Test, mean (SD)159.6 (88.7)286.8 (92.0)360.9 (87.1)<0.001

KCCQ Subdomain Scores by SPPB Category
Severe Limitations (n=65)Mild Limitations (n =84)No Limitations (n=52)P value
KCCQ Overall, mean (SD)56.2 (21.3)69.3 (22.5)75.6 (21.4)<0.001
Physical Limitation52.2 (26.2)69.7 (24.3)75.4 (25.9)<0.001
Symptom Stability50.8 (18.7)53.9 (22.5)56.7 (24.3)0.339
Symptom Frequency54.6 (25.0)72.3 (26.3)77.2 (23.0)<0.001
Symptom Burden61.9 (26.9)75.9 (24.1)80.6 (23.2)<0.001
Self-Efficacy72.7 (27.0)76.2 (23.8)76.7 (28.0)0.637
Quality of Life55.1 (24.9)65.3 (25.9)70.0 (24.2)0.005
Social Limitations58.4 (28.6)67.9 (31.1)77.4 (26.7)0.005
Introduction: Functional status is associated with poor health outcomes, including quality of life. The Short Physical Performance Battery (SPPB) is commonly used to assess functional status. However, there are limited data describing quantifiable functional status limitations in Black and Hispanic patients with stable congestive heart failure. We hypothesized that in a Black and Hispanic outpatient population with heart failure, low functional capacity, as determined by low SPPB score, would be associated with worse quality of life.
Methods: The multicenter, prospective, Screening for Cardiac Amyloidosis in Minority Populations (SCAN-MP) study identified Black and Hispanic subjects with heart failure, collected baseline characteristics, and measured SPPB. Quality of life was measured by the Kansas City Cardiomyopathy Questionnaire (KCCQ). SPPB scores were stratified into severe functional deficit (0-6), mild functional deficit (7-9) and no functional deficit (10-12).
Results: Of 220 patients in the study, 201 (91.3%) completed the SPPB. SPPB score was associated with the overall KCCQ score and with multiple subdomains of the KCCQ, but not exclusively with physical limitation (Table 1). Patients with low SPPB scores were more likely to be older, female, have higher BMI and NYHA class, less education, more comorbidities, and worse Six-Minute Walk Test (Table 2).
Conclusion: Among Black and Hispanic outpatients with stable heart failure, stepwise decrements in functional status, as defined by the SPPB, are associated with overall KCCQ score, and scores across a variety of sub-domains. These findings suggest that targeted interventions to improve patients’ functional status could broadly benefit quality of life.
Baseline Characteristics by SPPB Category
Severe Limitations (n=65)Mild Limitations (n=84)No Limitations (n=52)P value
Age, mean (SD)73.9 (7.9)71.2 (8.7)69.6 (7.5)0.016
Gender, n (%)<0.001
Male24 (36.9)51 (60.7)37 (71.2)
Female41 (63.1)33 (39.3)15 (28.8)
BMI, mean (SD)35.2 (8.2)32.0 (6.7)33.0 (7.3)0.030
Education, n (%)0.016
Less Than High School32 (50.0)22 (26.5)11 (21.6)
High School23 (35.9)33 (39.8)22 (43.1)
College6 (9.4)22 (26.5)15 (29.4)
Graduate3 (4.7)4 (4.8)3 (5.9)
Number of Comorbidities, mean (SD)6.5 (1.7)5.9 (2.0)5.1 (1.8)<0.001
Echo Left Ventricular Ejection Fraction, mean (SD)55.1 (14.0)58.3 (10.6)54.0 (11.1)0.106
NYHA Class (%)<0.001
Class I4 (6.2)18 (21.7)15 (28.8)
Class II28 (43.8)46 (55.4)32 (61.5)
Class III31 (48.4)19 (22.9)5 (9.6)
Class IV1 (1.6)0 (0.0)0 (0.0)
Six-Minute Walk Test, mean (SD)159.6 (88.7)286.8 (92.0)360.9 (87.1)<0.001

KCCQ Subdomain Scores by SPPB Category
Severe Limitations (n=65)Mild Limitations (n =84)No Limitations (n=52)P value
KCCQ Overall, mean (SD)56.2 (21.3)69.3 (22.5)75.6 (21.4)<0.001
Physical Limitation52.2 (26.2)69.7 (24.3)75.4 (25.9)<0.001
Symptom Stability50.8 (18.7)53.9 (22.5)56.7 (24.3)0.339
Symptom Frequency54.6 (25.0)72.3 (26.3)77.2 (23.0)<0.001
Symptom Burden61.9 (26.9)75.9 (24.1)80.6 (23.2)<0.001
Self-Efficacy72.7 (27.0)76.2 (23.8)76.7 (28.0)0.637
Quality of Life55.1 (24.9)65.3 (25.9)70.0 (24.2)0.005
Social Limitations58.4 (28.6)67.9 (31.1)77.4 (26.7)0.005
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